Review



human normal immortalized hepatocyte cell line  (ATCC)


Bioz Verified Symbol ATCC is a verified supplier
Bioz Manufacturer Symbol ATCC manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
  • 96

    Structured Review

    ATCC human normal immortalized hepatocyte cell line
    Human Normal Immortalized Hepatocyte Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 263 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/THLE-3/pm41990932-57-0-18
    Average 96 stars, based on 263 article reviews
    human normal immortalized hepatocyte cell line - by Bioz Stars, 2026-10
    96/100 stars

    Images

    Related Articles

    Expressing:

    Article Title: Integrative metabolomics highlights gut microbiota metabolites as novel NAFLD-related candidate biomarkers in children
    Article Snippet: The plasma levels of IL-1β, IL-6, IL-12, IL-17, IL-21, IL-32, TNF-α, and CXCL8 were measured using enzyme linked immunosorbent assay (ELISA) kits (Renjiebio, China) by Tecan Enzyme tag analyzer (Infinite F50, Switzerland). .. Human normal hepatocyte cell line hepatocytes (THLE-3) were obtained from American Type Culture Collection (Manassas, Virginia, USA), which were non-tumorigenic and negative for alpha fetoprotein expression. .. The cells were cultured in RPMI-1640 medium (GE Health Life Sciences, USA) supplemented with 10% (vol/ vol) fetal bovine serum (Gibco, USA), and 1% penicillin/streptomycin (100 IU/mL penicillin and 100 mg/mL streptomycin) (Gibco, USA) at 37°C in a humidified atmosphere of 5% CO 2 (Thermo Fisher Scientific, USA).

    Article Title: Targeted metabolomics reveals bioactive inflammatory mediators from gut into blood circulation in children with NAFLD.
    Article Snippet: .. Human normal hepatocyte cell line hepatocytes (THLE-3) were obtained from the American Type Culture Collection (Manassas, Virginia, USA), which is non-tumorigenic and alpha fetoprotein expression negative. .. The cells were cultured in RPMI-1640 medium (GE Health Life Sciences, USA) supplemented with 10% (vol/ vol) fetal bovine serum (FBS) (Gibco, USA), and 1% penicillin/streptomycin (100 IU/ml penicillin and 100mg/ml streptomycin) (Gibco, USA) at 37 °C in a humidified atmosphere of 5% CO2.We terminatedwith 0.25% trypsin-EDTA (Gibco, USA) and collected logarithm growth cells.

    Article Title: Targeted metabolomics reveals bioactive inflammatory mediators from gut into blood circulation in children with NAFLD
    Article Snippet: .. Human normal hepatocyte cell line hepatocytes (THLE-3) were obtained from the American Type Culture Collection (Manassas, Virginia, USA), which is non-tumorigenic and alpha fetoprotein expression negative. .. The cells were cultured in RPMI-1640 medium (GE Health Life Sciences, USA) supplemented with 10% (vol/ vol) fetal bovine serum (FBS) (Gibco, USA), and 1% penicillin/streptomycin (100 IU/ml penicillin and 100 mg/ml streptomycin) (Gibco, USA) at 37 °C in a humidified atmosphere of 5% CO 2 .

    Article Title: Integrative metabolomics highlights gut microbiota metabolites as novel NAFLD-related candidate biomarkers in children.
    Article Snippet: The plasma levels of IL-1β, IL-6, IL-12, IL-17, IL-21, IL-32, TNF-α, and CXCL8 were measured using enzyme linked immunosorb ent assay (ELISA) kits (Renjiebio, China) by Tecan Enzyme tag analyzer (Infinite F50, Switzerland). .. Human normal hepatocyte cell line hepatocytes (THLE-3) were obtained from American Type Culture Collection (Manassas, Virginia, USA), which were non-tumorigenic and negative for alpha fetoprotein expression. .. The cells were cultured in RPMI-1640 medium (GE Health Life Sciences, USA) supplemented with 10% (vol/ vol) fetal bovine serum (Gibco, USA), and 1% penicillin/streptomycin (100 IU/mL penicillin and 100 mg/mL streptomycin) (Gibco, USA) at 37°C in a humidified atmosphere of 5% CO2 (Thermo Fisher Scientific, USA).



    Similar Products

    96
    ATCC human normal immortalized hepatocyte cell line
    Human Normal Immortalized Hepatocyte Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/THLE-3/pm41990932-57-0-18
    Average 96 stars, based on 1 article reviews
    human normal immortalized hepatocyte cell line - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    96
    ATCC human normal hepatocyte cell line hepatocytes
    Human Normal Hepatocyte Cell Line Hepatocytes, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/THLE-3/pm40593862-222-0-11
    Average 96 stars, based on 1 article reviews
    human normal hepatocyte cell line hepatocytes - by Bioz Stars, 2026-10
    96/100 stars
      Buy from Supplier

    90
    iCell Bioscience Inc hl-7702 cells (human normal hepatocyte cell line)
    Hl 7702 Cells (Human Normal Hepatocyte Cell Line), supplied by iCell Bioscience Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/l02+cells/pm39884472-55-0-26
    Average 90 stars, based on 1 article reviews
    hl-7702 cells (human normal hepatocyte cell line) - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Servicebio Inc human normal hepatocyte cell line lo2
    Analysis of the expression of POC1A in various classifications of HCC patients, as well as in HCC and liver cancer cell lines. (A) Comparison of POC1A between cancer tissue samples and normal tissue samples. (B) Comparison of the expression of POC1A in different genders. (C) Comparison of the expression of POC1A in different age groups. (D) The expression levels of POC1A were all higher in the Caucasian, African-American, and Asian HCC patients than the normal patients. The expression of POC1A was significantly higher in LIHC tissue samples from Asian patients than LIHC tissue samples from Caucasian patients. (E) The expression of POC1A in individual cancer stages. (F) The expression of POC1A in different transistor grades. (G) The expression of POC1A in tumor (T) stage. (H) The expression of POC1A in node (N) stage. (I) The expression of POC1A in metastasis (M) stage. (J) Analysis of POC1A expression in normal liver tissue and cancer tissue samples from patients with hepatocellular carcinoma using immunohistochemical methods in the Human Protein Atlas database. Liver sample: https://www.proteinatlas.org/ENSG00000164087-POC1A/tissue/liver#img , hepatocellular samples: https://www.proteinatlas.org/ENSG00000164087-POC1A/pathology/liver+cancer#img . Scale bar: 100 µm. (K) Analysis of POC1A mRNA expression in <t>LO2</t> and HepG2 cell lines by qPCR assay. *, P<0.05; **, P<0.01; -: no significance. TCGA, The Cancer Genome Atlas; HCC, hepatocellular carcinoma; LIHC, liver hepatocellular carcinoma; mRNA, messenger RNA; qPCR, quantitative polymerase chain reaction; POC1A , POC1 centriolar protein A.
    Human Normal Hepatocyte Cell Line Lo2, supplied by Servicebio Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/human+normal+hepatocyte+cell+line+lo2/pmc11483421-94-2-7
    Average 90 stars, based on 1 article reviews
    human normal hepatocyte cell line lo2 - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Beyotime human normal hepatocyte cell line hl7702
    Analysis of the expression of POC1A in various classifications of HCC patients, as well as in HCC and liver cancer cell lines. (A) Comparison of POC1A between cancer tissue samples and normal tissue samples. (B) Comparison of the expression of POC1A in different genders. (C) Comparison of the expression of POC1A in different age groups. (D) The expression levels of POC1A were all higher in the Caucasian, African-American, and Asian HCC patients than the normal patients. The expression of POC1A was significantly higher in LIHC tissue samples from Asian patients than LIHC tissue samples from Caucasian patients. (E) The expression of POC1A in individual cancer stages. (F) The expression of POC1A in different transistor grades. (G) The expression of POC1A in tumor (T) stage. (H) The expression of POC1A in node (N) stage. (I) The expression of POC1A in metastasis (M) stage. (J) Analysis of POC1A expression in normal liver tissue and cancer tissue samples from patients with hepatocellular carcinoma using immunohistochemical methods in the Human Protein Atlas database. Liver sample: https://www.proteinatlas.org/ENSG00000164087-POC1A/tissue/liver#img , hepatocellular samples: https://www.proteinatlas.org/ENSG00000164087-POC1A/pathology/liver+cancer#img . Scale bar: 100 µm. (K) Analysis of POC1A mRNA expression in <t>LO2</t> and HepG2 cell lines by qPCR assay. *, P<0.05; **, P<0.01; -: no significance. TCGA, The Cancer Genome Atlas; HCC, hepatocellular carcinoma; LIHC, liver hepatocellular carcinoma; mRNA, messenger RNA; qPCR, quantitative polymerase chain reaction; POC1A , POC1 centriolar protein A.
    Human Normal Hepatocyte Cell Line Hl7702, supplied by Beyotime, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/trizol+reagent/pmc11483456-92-0-16
    Average 90 stars, based on 1 article reviews
    human normal hepatocyte cell line hl7702 - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    iCell Bioscience Inc normal human hepatocytes cell line wrl68
    Analysis of the expression of POC1A in various classifications of HCC patients, as well as in HCC and liver cancer cell lines. (A) Comparison of POC1A between cancer tissue samples and normal tissue samples. (B) Comparison of the expression of POC1A in different genders. (C) Comparison of the expression of POC1A in different age groups. (D) The expression levels of POC1A were all higher in the Caucasian, African-American, and Asian HCC patients than the normal patients. The expression of POC1A was significantly higher in LIHC tissue samples from Asian patients than LIHC tissue samples from Caucasian patients. (E) The expression of POC1A in individual cancer stages. (F) The expression of POC1A in different transistor grades. (G) The expression of POC1A in tumor (T) stage. (H) The expression of POC1A in node (N) stage. (I) The expression of POC1A in metastasis (M) stage. (J) Analysis of POC1A expression in normal liver tissue and cancer tissue samples from patients with hepatocellular carcinoma using immunohistochemical methods in the Human Protein Atlas database. Liver sample: https://www.proteinatlas.org/ENSG00000164087-POC1A/tissue/liver#img , hepatocellular samples: https://www.proteinatlas.org/ENSG00000164087-POC1A/pathology/liver+cancer#img . Scale bar: 100 µm. (K) Analysis of POC1A mRNA expression in <t>LO2</t> and HepG2 cell lines by qPCR assay. *, P<0.05; **, P<0.01; -: no significance. TCGA, The Cancer Genome Atlas; HCC, hepatocellular carcinoma; LIHC, liver hepatocellular carcinoma; mRNA, messenger RNA; qPCR, quantitative polymerase chain reaction; POC1A , POC1 centriolar protein A.
    Normal Human Hepatocytes Cell Line Wrl68, supplied by iCell Bioscience Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/normal+human+hepatocytes+cell+line+wrl68/pm39029315-49-0-9
    Average 90 stars, based on 1 article reviews
    normal human hepatocytes cell line wrl68 - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    90
    Procell Inc human normal hepatocyte cell line l-o2
    Analysis of the expression of POC1A in various classifications of HCC patients, as well as in HCC and liver cancer cell lines. (A) Comparison of POC1A between cancer tissue samples and normal tissue samples. (B) Comparison of the expression of POC1A in different genders. (C) Comparison of the expression of POC1A in different age groups. (D) The expression levels of POC1A were all higher in the Caucasian, African-American, and Asian HCC patients than the normal patients. The expression of POC1A was significantly higher in LIHC tissue samples from Asian patients than LIHC tissue samples from Caucasian patients. (E) The expression of POC1A in individual cancer stages. (F) The expression of POC1A in different transistor grades. (G) The expression of POC1A in tumor (T) stage. (H) The expression of POC1A in node (N) stage. (I) The expression of POC1A in metastasis (M) stage. (J) Analysis of POC1A expression in normal liver tissue and cancer tissue samples from patients with hepatocellular carcinoma using immunohistochemical methods in the Human Protein Atlas database. Liver sample: https://www.proteinatlas.org/ENSG00000164087-POC1A/tissue/liver#img , hepatocellular samples: https://www.proteinatlas.org/ENSG00000164087-POC1A/pathology/liver+cancer#img . Scale bar: 100 µm. (K) Analysis of POC1A mRNA expression in <t>LO2</t> and HepG2 cell lines by qPCR assay. *, P<0.05; **, P<0.01; -: no significance. TCGA, The Cancer Genome Atlas; HCC, hepatocellular carcinoma; LIHC, liver hepatocellular carcinoma; mRNA, messenger RNA; qPCR, quantitative polymerase chain reaction; POC1A , POC1 centriolar protein A.
    Human Normal Hepatocyte Cell Line L O2, supplied by Procell Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+normal+hepatocyte+cell+line+hepatocytes/human+normal+liver+cell+line+lo2/pmc11046247-37-0-18
    Average 90 stars, based on 1 article reviews
    human normal hepatocyte cell line l-o2 - by Bioz Stars, 2026-10
    90/100 stars
      Buy from Supplier

    Image Search Results


    Analysis of the expression of POC1A in various classifications of HCC patients, as well as in HCC and liver cancer cell lines. (A) Comparison of POC1A between cancer tissue samples and normal tissue samples. (B) Comparison of the expression of POC1A in different genders. (C) Comparison of the expression of POC1A in different age groups. (D) The expression levels of POC1A were all higher in the Caucasian, African-American, and Asian HCC patients than the normal patients. The expression of POC1A was significantly higher in LIHC tissue samples from Asian patients than LIHC tissue samples from Caucasian patients. (E) The expression of POC1A in individual cancer stages. (F) The expression of POC1A in different transistor grades. (G) The expression of POC1A in tumor (T) stage. (H) The expression of POC1A in node (N) stage. (I) The expression of POC1A in metastasis (M) stage. (J) Analysis of POC1A expression in normal liver tissue and cancer tissue samples from patients with hepatocellular carcinoma using immunohistochemical methods in the Human Protein Atlas database. Liver sample: https://www.proteinatlas.org/ENSG00000164087-POC1A/tissue/liver#img , hepatocellular samples: https://www.proteinatlas.org/ENSG00000164087-POC1A/pathology/liver+cancer#img . Scale bar: 100 µm. (K) Analysis of POC1A mRNA expression in LO2 and HepG2 cell lines by qPCR assay. *, P<0.05; **, P<0.01; -: no significance. TCGA, The Cancer Genome Atlas; HCC, hepatocellular carcinoma; LIHC, liver hepatocellular carcinoma; mRNA, messenger RNA; qPCR, quantitative polymerase chain reaction; POC1A , POC1 centriolar protein A.

    Journal: Translational Cancer Research

    Article Title: Analysis of the role of POC1A in the development and progression of hepatocellular carcinoma

    doi: 10.21037/tcr-23-2398

    Figure Lengend Snippet: Analysis of the expression of POC1A in various classifications of HCC patients, as well as in HCC and liver cancer cell lines. (A) Comparison of POC1A between cancer tissue samples and normal tissue samples. (B) Comparison of the expression of POC1A in different genders. (C) Comparison of the expression of POC1A in different age groups. (D) The expression levels of POC1A were all higher in the Caucasian, African-American, and Asian HCC patients than the normal patients. The expression of POC1A was significantly higher in LIHC tissue samples from Asian patients than LIHC tissue samples from Caucasian patients. (E) The expression of POC1A in individual cancer stages. (F) The expression of POC1A in different transistor grades. (G) The expression of POC1A in tumor (T) stage. (H) The expression of POC1A in node (N) stage. (I) The expression of POC1A in metastasis (M) stage. (J) Analysis of POC1A expression in normal liver tissue and cancer tissue samples from patients with hepatocellular carcinoma using immunohistochemical methods in the Human Protein Atlas database. Liver sample: https://www.proteinatlas.org/ENSG00000164087-POC1A/tissue/liver#img , hepatocellular samples: https://www.proteinatlas.org/ENSG00000164087-POC1A/pathology/liver+cancer#img . Scale bar: 100 µm. (K) Analysis of POC1A mRNA expression in LO2 and HepG2 cell lines by qPCR assay. *, P<0.05; **, P<0.01; -: no significance. TCGA, The Cancer Genome Atlas; HCC, hepatocellular carcinoma; LIHC, liver hepatocellular carcinoma; mRNA, messenger RNA; qPCR, quantitative polymerase chain reaction; POC1A , POC1 centriolar protein A.

    Article Snippet: The human normal hepatocyte cell line LO2 (Servicebio Technology Co., Ltd., Wuhan, China) was cultured in Roswell Park Memorial Institute 1640 medium, and the hepatoma cell line HepG2 (Procell Life Science & Technology Co., Ltd., Wuhan, China) was cultured in Dulbecco’s Modified Eagle Medium (Hyclone, Thermo Fisher Scientific Inc., Waltham, MA), supplemented with 10% fetal bovine serum and antibiotics (10,000 U/mL penicillin and 10 mg/mL streptomycin) (Procell Life Science & Technology Co., Ltd.).

    Techniques: Expressing, Comparison, Immunohistochemical staining, Real-time Polymerase Chain Reaction